Peeling agents based on TCA (trichloroacetic acid) have long been used in aesthetic medicine to stimulate skin renewal through a controlled chemical damage. This approach can offer visible results in the short term, but presents biological challenges that deserve deeper reflection, especially in terms of long-term skin health.

An effective but non-physiological mechanism

TCA acts through irreversible protein denaturation, coagulating the superficial epidermal and dermal proteins. This is a non-selective process that induces a strong inflammatory response, increasing oxidative stress and pro-inflammatory mediators. If repeated over time, it can compromise barrier function and accelerate the processes of inflamm-aging.

High concentrations and chemical compensations

Many biorivitalizing peels on the market use high percentages of TCA (33%-35%), obviously buffered with substances like ammonia or other strongly oxidative agents. These compensations, while reducing immediate aggressiveness, create a biologically stressful skin environment, with disorganization of the extracellular matrix and chronic fibroblastic distress.

Skin Longevity: a paradigm shift

The concept of Skin Longevity shifts the focus from the immediate effect to the preservation of the skin's biological capital. The goal is no longer to provoke a forced reaction, but to stimulate a physiological, progressive, and sustainable response.

The MEDEA approach

In this vision fits 3PH ExoPeel, a system that avoids chemical necrosis and toxic compensations, promoting a controlled biological activation. Thanks to a multi-phase technology and advanced biotechnological actives, it supports regeneration and turnover while fully respecting skin physiology.

Rethinking peeling

Today, peeling should not be an aggressive act, but a conscious act of care. An approach oriented towards Skin Longevity allows for real results, protecting the skin over time and building a healthier, more lasting, and resilient beauty.